個人簡介
黃威🤏🏽,理學博士,中國科沐鸣2上海免疫與感染研究所研究員♻、課題組組長🎠。2014年於中國科沐鸣2大學獲得博士學位,2014年至2023年先後在美國羅格斯大學羅伯特醫沐鸣2和約翰斯霍普金斯大學公共衛生沐鸣2進行博士後研究和擔任副研究員。在Science、eLife、PLoS neglected tropical diseases、Philosophical Transactions of the Royal Society B、mBio等雜誌發表論文20篇,引用次數1600余次🧑🎄。
研究方向
1.研究包括共生細菌和轉基因蚊蟲在內的蚊媒傳染病的阻斷策略;
2.研究蚊媒病原對於蚊蟲🔧、哺乳動物等宿主的侵染和宿主的防禦機製;
3.研究針對蚊媒病原的高效疫苗和治療藥物;
4.研究控製蚊蟲種群數量的生物防治策略。
榮譽及獲獎情況
主持與承擔主要項目情況
發表論著情況
Huang, W., Rodrigues, J., Bilgo, E., Tormo, J. R., Challenger, J. D., De Cozar-Gallardo, C., ... & Jacobs-Lorena, M. (2023). Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes. Science, 381(6657), 533-540. (IF= 63.82, 一區).
Huang W., Vega-Rodriguez J., Kizito C., Jacbos-Lorena M. (2022). Combining transgenesis with paratransgenesis to fight malaria. elife, (IF=8.14, 生物學一區)
Huang, W*., Fu, K., Gao, Q., Tejo, R. P., Floeter-Winter, L. M., & Gutierrez, A. P. (Eds.). (2022). Host-microbe interaction and coevolution. Frontiers Media SA (Editorial for Frontiers in Microbiologyand Frontiers in Genetics).
Huang W, Cha S J, Jacobs‐Lorena M. New weapons to fight malaria transmission: A historical view. Entomological Research, 2022. (IF=1.358, 生物學三區)
Huang W., Wang S., Jacbos-Lorena M. (2020). Self-limiting Paratransgenesis. PLOS Neglected Tropical Diseases (IF=4.411, 熱帶醫學一區)
Huang, W., Wang, S., & Jacobs-Lorena, M. (2020). Use of Microbiota to Fight Mosquito-Borne Disease. Frontiers in Genetics, 11. (IF=4.274, 生物學二區)
Huang, W., Hong, S., Tang, G., Lu, Y., & Wang, C. (2019). Unveiling the function and regulation control of the DUF3129 family proteins in fungal infection of hosts. Philosophical Transactions of the Royal Society B, 374(1767), 20180321. (IF=6.237, 生物學一區).
Huang, W., Liao, G., Baker, G. M., Wang, Y., Lau, R., Paderu, P., ... & Xue, C. (2016). Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans. mBio, 7(3), e00478-16(IF=7.867, 生物學一區).
Huang W., Shang Y. F., Chen P. L., Cen K., & Wang, C. S. (2015). Basic leucine zipper (bZIP) domain transcription factor MBZ1 regulates cell wall integrity, spore adherence, and virulence in Metarhizium robertsii. Journal of Biological Chemistry, 290(13), 8218-8231(IF=5.486, 生物學二區).
Huang W., Shang Y. F., Chen P. L., Gao Q., Wang C. S. (2015). MrpacC regulates sporulation, insect cuticle penetration and immune evasion in Metarhizium robertsii.Environmental Microbiology, 17(4), 994-1008(IF=5.491, 生物學二區).
Huang W., Zhang Y. H., Chen D. Q., Hu H. Q., Zhuang G. Q. (2009). Degradation and Remaining of the Bt Protein in Several Soils. Journal of Huazhong Agricultural University, 28(2): 169-173. (In Chinese)
其他發表論文
Godoy, R. S. M., Barbosa, R. C., Huang, W., Secundino, N. F. C., Pimenta, P. F. P., Jacobs-Lorena, M., & Martins, G. F. (2023). The larval midgut of Anopheles, Aedes, and Toxorhynchites mosquitoes (Diptera, Culicidae): a comparative approach in morphophysiology and evolution. Cell and Tissue Research, 1-24. (IF= 4.06, 三區).
Pascini, T. V., Jeong, Y. J., Huang, W., Pala, Z. R., Sá, J. M., Wells, M. B., ... & Vega-Rodríguez, J. (2022). Transgenic Anopheles mosquitoes expressing human PAI-1 impair malaria transmission. Nature communications, 13(1), 1-16.(IF=14.919, 生物學一區)
Gao, H., Bai, L., Jiang, Y., Huang, W., Wang, L., Li, S., ... & Wang, S. (2021). A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase. Nature Microbiology, 1-12. (IF=17.745, 生物學一區)
Wang, S., Dos-Santos, A. L., Huang, W., Liu, K. C., Oshaghi, M. A., Wei, G., ... & Jacobs-Lorena, M. (2017). Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria. Science, 357(6358), 1399-1402. (IF= 63.82, 一區).
Gao, Q., Lu, Y., Yao, H., Xu, Y. J., Huang, W., & Wang, C. S. (2016). Phospholipid homeostasis maintains cell polarity, development and virulence in Metarhizium robertsii. Environmental Microbiology, 18(11), 3976-3990(IF=5.491, 生物學二區).
Duan Z.B., Chen Y. X., Huang W.,Shang Y. F., Chen P. L., Wang C. S. (2013). Linkage of autophagy to fungal development, lipid storage and virulence in Metarhizium robertsii. Autophagy, 9(4), 538-549(IF=16.061, 生物學一區).
Gao Q*., Shang Y. F*., Huang W., Wang C. S. (2013). Glycerol-3-phosphate acyltransferase contributes to triacylglycerol biosynthesis, lipid droplet formation and host invasion in Metarhizium robertsii. Applied and Environmental Microbiology, 79, 7646-7653(IF=4.792, 生物學二區).
Shang Y. F., Duan Z. B., Huang W., Gao Q., Wang C. S. (2012). Improving UV resistance and virulence of Beauveria bassiana by genetic engineering with an exogenous tyrosinase gene. Journal of Invertebrate Pathology, 109(1), 105-109(IF=2.841, 生物學二區).
Gao Q., Jin K., Ying S. H., Zhang Y. J., Xiao G. H., Shang Y. F., Duan Z. B., Hu X., Xie X. Q., Zhou G., Peng G. X., Luo Z. B., Huang W., Wang B., Fang W. G., Wang S. B., Zhong Y., Ma L.J., St. Leger R. J., Zhao G. P., Pei Y., Feng M. G., Xia Y. X. and Wang C. S. (2011). Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum.PLoS Genetics, 7(1), e1001264
Zhang Y. H., Huang W., Hu H. Q., Liu Y. R., Chen D. Q. (2007). Remaining Dynamics of Cry1Ab Proteins from Transgenic Bt Corn in Soils. Journal of Huazhong Agricultural University, 26(2), 485-490. (In Chinese)
聯系方式
Email🧽:whuang@siii.cas.cn
辦公地址:上海市徐匯區嶽陽路320號新生命科學大樓B511